学部・大学院
Academics

相馬 亜希子

相馬 亜希子 助教 博士(農学)

氏名

相馬 亜希子

職位

助教

学位

博士(農学)

所属
  • 園芸学研究科 生物資源科学コース 応用生命化学領域 生命分子化学分野
  • 園芸学部 応用生命化学科 応用生命化学プログラム 生命分子化学分野
居室 C棟 1階 101
電話 047-308-8871
Fax 047-308-8720
E-mail soma@
chiba-u.jp
ホームページ http://www.h.chiba-u.jp/lab/bunsei/index.html

東京生まれ、秋田育ち。弘前大学理学部卒業、同大学院理学研究科修士課程修了、岩手大学大学院博士課程修了。理化学研究所(ERATO)、分子細胞生物学研究所、立教大学を経て、2011年4月より現職。専門は微生物を用いた分子生物学。趣味は音楽鑑賞、読書。学生の頃より、tRNAをはじめとした機能性低分子RNAおよびその遺伝子の研究を行っています。「RNA分子」の機能と進化に着目し、「生命」という精緻な分子システムがどのような仕組みで成り立っているかを解明したいと考えています。

主な業績

  • Akiko Soma. Circularly permuted tRNA genes; their expression, processing, and development. (2014) Frontiers in Genetics, 5:36. eCollection.
  • Naoki Sudo, Akiko Soma, Sunao Iyoda, Akira Muto, Mayumi Suh, Nanako Kurihara, Makoto Ohnishi, Yoshitoshi Ogura, Tetsuya Hayashi, Hiroyuki Abe, Toru Tobe, Ken Kurokawa, and Yasuhiko Sekine. A novel small regulatory RNA Esr41 accelerates cell motility in enterohaemorrhagic Escherichia coli O157. (2014) J. General and Applied Microbiology, (60, 44-50.
  • Akiko Soma, Junichi Sugahara, Akinori Onodera, Nozomu Yachie, Akio Kanai, Satoru Watanabe, Hirofumi Yoshikawa, Mio Ohnuma, Haruko Kuroiwa, Tsuneyoshi Kuroiwa, and Yasuhiko Sekine. Identification of highly-disrupted tRNAs in nuclear genome of the red alga, Cyanidioschyzon merolae 10D. (2013) Scientific Reports, 3, 2321-2329.
  • Akiko Soma. Identification and functional analysis of non-coding RNA from hemorrhagic Escherichia coli O157:H7 sakai. (2011) Inst. Ferment. Res. Comm., 25, 93-105.
  • Akiko Soma. Permuted tRNA genes expressed via a circular RNA intermediate in Cyanidioschyzon merolae. (2009) J. Jpn. Soc. Extremophiles, 8, 11-14.
  • Akiko Soma, Akinori Onodera, Junichi Sugahara, Akio Kanai, Nozomu Yachie, Masaru Tomita, Fujio Kawamura, and Yasuhiko Sekine. Permuted tRNA genes expressed via a circular RNA intermediate in Cyanidioschyzon merolae. (2007) Science, 318, 450-453.
  • Junichi Sugahara, Yachie Nozomu, Yasuhiko Sekine, Akiko Soma, Matsui, Masaru Tomita, and Akio Kanai. SPLITS: a new program for predicting split and intron-containing tRNA genes at the genome level. (2006) In Silico Biol., 6, 411-418.
  • Yoshiho Ikeuchi, Akiko Soma, Tomotake Ote, Jun-ichi Kato, Yasuhiko Sekine and Tsutomu Suzuki. Molecular mechanism of lysidine synthesis, which determines tRNA identity and codon recognition. (2005) Mol. Cell, 19, 235-246.
  • Kotaro Nakanishi, Shuya Fukai, Yoshiho Ikeuchi, Akiko Soma, Yasuhiko Sekine, Tsutomu Suzuki, and Osamu Nureki. Structural basis for lysidine formation by ATP pyrophosphatase accompanied with a lysine-specific loop and a tRNA-recognition domain. (2005) Proc. Natl. Acad. Sci. USA, 102, 7487-7492.
  • Akiko Soma, Yoshiho Ikeuchi, Satoru Kanemasa, Kazuo Kobayashi, Naotake Ogasawara, Tomotake Ote, Jun-ichi Kato, Kimitsuna Watanabe, Yasuhiko Sekine and Tsutomu Suzuki An RNA-modifying enzyme that governs both codon and amino acid specificities of isoleucine tRNA. (2003) Mol. Cell, 12, 689-698.
  • Kensaku Sakamoto, Akiko Hayashi, Ayako Sakamoto, Daisuke Kiga, Hiroshi Nakayama, Akiko Soma, Takatsugu Kobayashi, Makoto Kitabatake, Koji Takio, Kazuki Saito, Mikako Shirouzu, Ichiro Hirao, and Shigeyuki Yokoyama. Site-specific incorporation of an unnatural amino acid into proteins in mammalian cells. (2002) Nucleic Acids Res., 26, 4692-4699.
  • Akiko Soma, Kiyoto Uchiyama, Teruyuki Sakamoto, Miho Maeda, and Hyouta Himeno. Unique recognition style of tRNALeu by Haloferax volcanii leucyl-tRNA synthetase. (1999) J. Mol. Biol., 293, 1029-1038.
  • Akiko Soma and Hyouta Himeno. Cross-species aminoacylation of tRNA with a long variable arm between Escherichia coli and Saccharomyces cerevisiae. (1998) Nucleic Acids Res., 26, 4374-4381.
  • Hyouta Himeno , Shukuko Yoshida, Akiko Soma, and Kazuya Nishikawa. Only one nucleotide insertion to the long variable arm confers an efficient serine acceptor activity upon Saccharomyces cerevisiae tRNALeu in vitro. (1997) J. Mol. Biol., 268, 704-711.
  • Akiko Soma, Ritsuko Kumagai, Kazuya Nishikawa, and Hyouta Himeno. The anticodon loop is a major identity determinant of Saccharomyces cerevisiae tRNALeu. (1996) J. Mol. Biol., 263, 707-714.
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